https://www.nitricfollowup.com/home daily 1.0 2025-01-15 https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/dc96c3f0-6fc9-442e-b418-d26268eca5d4/GettyImages-182485671.jpg Home Difficulties in these areas may lead to poor school performance, relationship and behavioural issues. We already know some factors that might cause these problems. The factors that we know about only explain about 30% of child outcomes after cardiac surgery with 70% remaining a mystery at this time. https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/d4bde318-2926-42de-8c27-464e6eff7373/GettyImages-1201862098.jpg Home - This study has three components: Transcriptomic analyses Long-term follow-up Consumer engagement https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/6f9a1449-472a-4b18-a683-1d42cfac1fd9/PICOLO+Network+Logo+%281%29.png Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/602e91c9-a0f9-4329-a84c-bb6d32376b1c/ANZICS-LOGO-300x76.jpg Home - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.nitricfollowup.com/contact daily 0.75 2021-11-15 https://www.nitricfollowup.com/our-team daily 0.75 2025-01-15 https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952314075-3UI5BUVC5NBW3012Y5WJ/Hero-25.jpg Our Team - Prof Warwick Butt Paediatric Intensivist Co-Chair (Clinical), Steering Committee Royal Children’s Hospital, Melbourne Murdoch Children’s Research Institute https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952356604-VG8OXD0KJMSRBO4QHPX3/Schlapbach%2BPic.png Our Team - Prof Luregn Schlapbach Paediatric Intensivist Chief Investigator University Children’s Hospital, Zurich The University of Queensland https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952633054-KE8ECY9KIDYHK7WHAINA/7494.jpeg Our Team - Prof Kristen Gibbons Epidemiologist Biostatistician Co-Chair (Research), Steering Committee Co-Lead, Data Project Group The University of Queensland https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952684913-D0O2Z1IDPQ79TZH5RJ5W/picture-591-1595827790.jpg Our Team - Prof Vicki Anderson Neuropsychologist Co-Lead, Long-term Follow Up Project Group Murdoch Children’s Research Institute https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952546884-NXWPED76G5ELXGZF7A5Y/daf55c22288e20624122b21b5a321628.jpg Our Team - Prof John Beca Paediatric Intensivist Study Sites Representative, Steering Committee Starship Children’s Hospital, Auckland https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/bfc3e401-19b8-4369-aaa3-a4286ae5bc40/766A0040_1a_final_8x6.jpg Our Team - Prof Debbie Long Nurse Co-Lead, Long-term Follow Up Project Group Queensland University of Technology https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/6e85106e-5a84-4625-b70c-4def3cd5359e/Kate.jpg Our Team - Kate Masterson Nurse Co-Lead, Consumer Engagement Project Group Royal Children’s Hospital, Melbourne https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/2e8e24f4-b6de-4474-9b45-384598f7f52e/Headshot.jpg Our Team - Brian Rose Nurse Co-Lead, Consumer Engagement Project Group Deakin University https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636952768425-FH7K1SQRIDQK8Z144JG5/pplistimage.jfif Our Team - Prof Lachlan Coin Bioinformatician Co-Lead, Data Project Group The University of Melbourne https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/20fbaafa-0c86-4940-a94e-4eca6905a73d/UQ_CHRC_4th_May_2021_Anna_MacDonald_010.jpg Our Team - Dr Anna MacDonald Speech Therapist Research Manager The University of Queensland https://www.nitricfollowup.com/transcriptomic-analyses daily 0.75 2022-03-02 https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/17c444f4-3cb0-4fb6-9436-a6dbb007c84e/GettyImages-891713642.jpg Transcriptomic analyses - We can use these gene signals to predict the outcomes of CPB surgery. We can also use this information to develop novel diagnostics and intervention strategies. From the blood samples that were collected in the previous NITRIC study, we can perform these analyses. https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636956626972-N7JDTP5JF0HVNYHIBNQA/GettyImages-668824726.jpg Transcriptomic analyses - This allows a cell to follow the instructions in the DNA and produce the gene. Based on the conditions of the cell (example whether it is healthy or sick), some genes can be produced in large amounts and some might not even be produced. By measuring the amount of these genes, we can identify which genes are involved in postoperative outcomes. https://www.nitricfollowup.com/longterm-follow-up daily 0.75 2021-11-25 https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636956765887-UE54OOWPDY19ON83PP2W/GettyImages-1313145532.jpg Long-term follow up - Yearly screening Each year around the child’s birthday, until their 5th birthday, parents/carers will be asked to complete an online neurodevelopmental survey (to completed on any smart device, laptop or computer). This survey will consist of questions that assess aspects such as motor skills, problem solving, communication, social and emotional behaviour and quality of life. In addition, questions around the parent/carer’s health and wellbeing. After the completion of each annual online survey, we will provide the family and their nominated GP with a report of the survey results. https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/1636956923347-N4W5AAFPFVO11S5B0GS9/GettyImages-894463832.jpg Long-term follow up - Face-to-face assessment Families will be invited to participate in a face-to-face neurodevelopmental assessment around the child’s 5th birthday at the treating children’s hospital (or, if necessary, within their home if travel to their treating hospital is not possible). This assessment will consist of a 2-3 hour assessment with the treating hospital’s neuropsychology team. This assessment will provide a more comprehensive understanding of the child’s cognition, thinking, motor activity and behaviour, and is particularly important information as children start to navigate schooling. After this assessment, a report will be provided detailing the child’s development, which may be shared with healthcare and education providers. https://www.nitricfollowup.com/consumer-engagement daily 0.75 2021-11-25 https://images.squarespace-cdn.com/content/v1/6188a2e96469c0118fc97c13/f5f8a5b6-f326-4f2c-bcf4-33a78d4eb431/GettyImages-1277174418.jpg Consumer engagement